期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：2001
卷号：47
期号：5
页码：335-339
DOI：10.3177/jnsv.47.335
出版社：Center for Academic Publications Japan
摘要：The effect of dietary cyclodextrins on liver and serum lipids and cecal organic acid production was investigated. Male Wistar rats were fed a.basal diet and a diet contain-ing 5% of α-, β-, or γ-cyclodextrin. The body weight gain in rats fed the α-cyclodextrin diet was not significantly different from rats fed the other three kinds of diets. The feeding of di-etary α-cyclodextrin increased total lipid and phospholipids in the liver. β-Cyclodextrin sig-nificantly lowered serum total cholesterol and phospholipid levels compared with the basaldiet et al. A decrease in serum triacylglycerol levels was also observed in β-cyclodextrin-fed rats. Dietary α-cyclodextrin significantly increased the weight of cecal tissues and contents, and an approximate fourfold increase in acetate, propionate, and total organic acids was noted, indicating the fermentibility of β-cyclodextrin compared with the basal diet. It seems likely that the suppression of serum cholesterol levels by α- and, 3-cyclodextrins might be due to the increasing acetate and propionate productions in the cecum.
