期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1997
卷号：43
期号：6
页码：673-678
DOI：10.3177/jnsv.43.673
出版社：Center for Academic Publications Japan
摘要：Food antigens transferred into breast milk sometimes cause an allergic reaction in exclusively breast-fed infants. This study will show whether the intake of a whey hydrolysate formula for lactating women (MOM HA) can reduce the appearance of food antigens in breast milk. Lactating women in the MOM group ( n =12) consumed MOM HA as a substitute for cow's milk and those in the COW group ( n =13) consumed cow's milk for more than 4 months. After the ingestion of 200 mL of MOM HA and cow's milk by the women in the MOM and COW groups, respectively, the first breast milk samples were obtained and β-lactoglobulin was measured using enzyme-linked immunosorbent assay. The number of subjects with detectable f3-lactoglobulin (>0.1 ng/mL) in the MOM group was two (17%), which was significantly less than that in the COW group (11 subjects, 85%, p <0.01). The level of β-lactoglobulin was also lower in the MOM group than the COW group ( p <0.01). Subsequently, the women in the MOM group consumed cow's milk and those in the COW group consumed MOM HA for one week; then a second sampling was performed. β-Lactoglobulin was detected in three (25%) and 8 subjects (62%) in the MOM and COW groups, respectively. The level of β-lactoglobulin was still lower in the MOM group ( p <0.05). The consumption of whey hydrolysate formula by lactating women over a considerable time reduces the transfer of β-lactoglobulin into their breast milk, and the low level can be maintained even after inadvertent ingestion of cow's milk.
关键词：β-lactoglobulin;breast milk;food antigen;cow's milk;whey hydrolysate formula
