期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1995
卷号:41
期号:6
页码:707-711
DOI:10.3177/jnsv.41.707
出版社:Center for Academic Publications Japan
摘要:Methyl linoleate hydroperoxides (MLHPO), a model for lipid hydroperoxides, suppressed murine natural killer (NK) cell-mediated cytotoxicity to YAC-1 cells. When NK cells were cultured with MLHPO, the conjugation of NK cells and YAC-1 cells was not affected, but most of the conjugated NK cells could not lyse YAC-1 cells. These findings suggest that NK cell-mediated cytotoxicity can be suppressed by lipid hydroperoxides.