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  • 标题:Effect of Methyl Linoleate Hydroperoxides on Murine Natural Killer Cell-Mediated Cytotoxicity
  • 本地全文:下载
  • 作者:Motoko OARADA ; Nobuyuki KURITA ; Kiyoshi TERAO
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1995
  • 卷号:41
  • 期号:6
  • 页码:707-711
  • DOI:10.3177/jnsv.41.707
  • 出版社:Center for Academic Publications Japan
  • 摘要:Methyl linoleate hydroperoxides (MLHPO), a model for lipid hydroperoxides, suppressed murine natural killer (NK) cell-mediated cytotoxicity to YAC-1 cells. When NK cells were cultured with MLHPO, the conjugation of NK cells and YAC-1 cells was not affected, but most of the conjugated NK cells could not lyse YAC-1 cells. These findings suggest that NK cell-mediated cytotoxicity can be suppressed by lipid hydroperoxides.
  • 关键词:lipid peroxides;natural killer cells;cytotoxicity
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