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  • 标题:The Metabolic Conversion of 9, 11, 13-Eleostearic Acid (18:3) to 9, 11-Conjugated Linoleic Acid (18:2) in the Rat
  • 本地全文:下载
  • 作者:Tsuyoshi TSUZUKI ; Miki IGARASHI ; Michio KOMAI
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:2003
  • 卷号:49
  • 期号:3
  • 页码:195-200
  • DOI:10.3177/jnsv.49.195
  • 出版社:Center for Academic Publications Japan
  • 摘要:The presence of a significant amount of 9, 11-conjugated linoleic acid (CLA, 9, 11-18%2) was confirmed in the liver and plasma lipids of rats fed a 1% (w/w % of diet) eleo-stearic acid (ESA, 9, 11, 13-18 e 3 ) diet for 4 wk, The chemical structure of the 9, 11-CLA apparent in the tissue lipids was identified by gas chromatography-electron impact mass spectrometry after its conversion to a 4, 4-dimethyloxazoline derivative. The concentration of CLA in the total fatty acids of the liver and plasma lipids reached to about 1% for each in the CLA-supplemented rats, while reaching 3.2% and 2.5%, respectively, in the ESA-supplemented rats, The results suggest that α-ESA is metabolized partially to CLA via a delta 13-saturation reaction in the rat. Some biological activities observed in α-ESA-fed animals may be ascribed also to CLA that is formed from ESA in the body.
  • 关键词:eleostearic acid;conjugated trienoic acid;conjugated linoleic acid;tung oil;conjugated fatty acid
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