期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1992
卷号:38
期号:Special
页码:161-164
DOI:10.3177/jnsv.38.Special_161
出版社:Center for Academic Publications Japan
摘要:AA-2G is a new stable derivative of AsA which is efficiently synthesized by regioselective transglucosylation with α-glucosidase and CGTase. AA-2G serves as a vitamin C supplement in experimental animals. AA-2G is easily hydrolyzed in vivo by α-glucosidase and also synthesized as a metabolite under some specified conditions. AA-2G stimulates collagen synthesis in cultured fibroblasts and enhances antibody production in cultured splenocytes. AA-2G which has no cytotoxicity is a promising AsA derivative for medical and nutritional uses.