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  • 标题:Comparative Changes in Plasma and RBC α-Tocopherol after Administration of dl-α-Tocopheryl Acetate and d-α-Tocopherol
  • 本地全文:下载
  • 作者:Toru OGIHARA ; Yasuhiko NISHIDA ; Masayuki MIKI
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1985
  • 卷号:31
  • 期号:2
  • 页码:169-177
  • DOI:10.3177/jnsv.31.169
  • 出版社:Center for Academic Publications Japan
  • 摘要:Changes in plasma and RBC α-tocopherol after intravenous and oral administration of dl -α-tocopheryl acetate were investigated using vitamin E-deficient rats and were compared with those following the administration of d -α-tocopherol, which is the most active and natural form of tocopherol. 1. Intravenous administration: By the administration of dl -tocopheryl acetate, the elevated plasma tocopherol levels were higher at 6h than those elevated by d tocopherol, but the RBC tocopherol was lower 6 h after the infusion of dl -tocopheryl acetate than after d tocopherol infusion. The tocopheryl acetate incorporated into the RBCs remained for 24h after the administration of tocopheryl acetate, the acetate then becoming undetect-able in plasma. 2. Oral administration: The tocopherol elevated in plasma and RBC was only the α-form and not tocopheryl acetate. In both plasma and RBCs, tocopherol levels were higher after the administration of d tocopherol than after dl -tocopheryl acetate administration, and more was found in RBCs.
  • 关键词:vitamin E;tocopheryl acetate;plasma;RBC;hydrolysis
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