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  • 标题:Neurotransmitter Releasing Action of 6R-Tetrahydrobiopterin
  • 本地全文:下载
  • 作者:K. KOSHIMURA ; T. OHUE ; Y. WATANABE
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1992
  • 卷号:38
  • 期号:Special
  • 页码:505-509
  • DOI:10.3177/jnsv.38.Special_505
  • 出版社:Center for Academic Publications Japan
  • 摘要:We showed that 6R-BH4, a natural cofactor for aromatic amino acids hydroxylases, can stimulate exocytotic DA release independently of its cofactor activity, and ACh release via monoaminergic system. From these results, it is quite likely that 6R-BH4 plays an important role in the regulation of neuronal activity, as a modulator of neurotransmitter release as well as a cofactor for hydroxylases.
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