期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1991
卷号：37
期号：Supplement
页码：S65-S70
DOI：10.3177/jnsv.37.Supplement_S65
出版社：Center for Academic Publications Japan
摘要：Total body and regional bone mineral density (BMD) and bone mineral content (BMC) in obese patients and healthy controls were assessed by dual-photon absorptiometry (DPA) in this study. In both men and women, BMD values in total body, pelvis, upper and lower extremities were significantly ( p <0.05) higher in the obese group (body mass index>28) than in the non - obese group (body mass index<23). These BMD values correlated significantly with body weights and with percentages of body fat. In the obese group, 8 massively obese women were treated with an 8 - week very low calorie diet (VLCD), resulting in a 13.4kg of mean body weight reduction. Although BMC in total body and in pelvis were maintained, significant decreases of BMC in the upper (from 275±30 to 255±26 g) and lower (from 871±47 to 805±31 g) extremities were observed following the 8 - week VLCD treatment. These results suggest that body fat mass affects BMD and BMC preferentially in weight bearing bone, the changes of which are not always associated with changes in total body BMD or BMC.
关键词：total bone mineral density;regional bone mineral density;obesity;very low calorie diet
