期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1990
卷号：36
期号：6
页码：513-519
DOI：10.3177/jnsv.36.513
出版社：Center for Academic Publications Japan
摘要：In order to elucidate the existence of a hydrogen bond between α-tocopherol and phospholipids in bilayer liposomes, the effects of the presence or absence of α-tocopherol or its acetate on either the permeability of liposomes to chromate ions or the fluidity of liposomes composed of the different kinds of lecithin [egg yolk phosphatidylcholine (EPC), 1-oleoyl-2-palmitoylphosphatidylcholine (OPPC), or 1- O -oleyl-2- O -palmitylphosphatidylcholine (OPPCE)] were examined. From the results obtained, it was concluded that the hydroxyl group of α-tocopherol is hydrogen bonded to the carbonyl group of a fatty acid ester in the phospholipids of bilayer liposomes in order to retain α-tocopherol molecule in the space close to the surface of membranes formed by the unsaturated fatty acid moiety of phospholipids.
关键词：vitamin E;α-tocopherol;membrane stabilization;liposome;hydrogen bond
