期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1977
卷号:23
期号:5
页码:423-429
DOI:10.3177/jnsv.23.423
出版社:Center for Academic Publications Japan
摘要:WILLIAMS et al . ( 1 ) investigated the changes in amounts of total mitochondrial protein and cytochromes in the liver of rats fed a protein-free diet for a long period, and found that there was a marked similarity between changes in amount of total mitochondrial protein and that of cytochromes. Present experiments were performed to clarify whe-ther under a more mild protein-deficient state the relationships found by Williams are applicable or not by investigating the changes in contents of cytochromes per unit amount of mitochondrial protein when rats were fed a low casein diet. A 4% casein diet was used as a low casein diet, and a 25% casein diet was used as a control diet. Rats were fed the test diets for 70 to 90 days. The results show that the contents of all cytochromes a , b , and c 1+ c assayed and expressed as nmoles per mg of mitochondrial protein were significantly higher in rats fed a low casein diet than those in rats fed a control diet. These results suggest that relationships found by Williams in a severe protein-deficient state would not be applicable in a more mild protein-deficient state.