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  • 标题:Effects of Active Oxygen Scavengers on the Peroxidation of Linoleic Acid Catalyzed by Dehydro-L-Ascorbic Acid or Its Degradation Products
  • 本地全文:下载
  • 作者:Masanosuke TAKAGI ; Hiroshi ONODERA ; Ikuo MIYAMOTO
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1988
  • 卷号:34
  • 期号:1
  • 页码:141-149
  • DOI:10.3177/jnsv.34.141
  • 出版社:Center for Academic Publications Japan
  • 摘要:The addition of 1, 4-diazabicyclo-[2, 2, 2] octane (DABCO) (100mM) or 1, 2, -dihydroxybenzene-3, 5-disulfonic acid (Tiron) (1mM) to a reaction mixture containing 10mM linoleic acid (LA), 20% EtOH, and 135μM dehydroascorbic acid (DHA) as a catalyst suppressed LA per-oxidation, but the addition of mannitol (100mM), uric acid (100μM), and catalase (6.5 units) did not. DHA or 2, 3-diketo-L-gulonic acid (DKG) accelerated LA peroxidation, but the splitting products of DHA did not affect LA peroxidation. These results suggest that some specific radicals are liberated in the degradation of DHA or DKG.
  • 关键词:lipid peroxidation;dehydroascorbic acid;active oxygen scavengers;DABCO;Tiron;2, 3-diketogulonic acid
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