期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1985
卷号：31
期号：6
页码：553-561
DOI：10.3177/jnsv.31.553
出版社：Center for Academic Publications Japan
摘要：The hepatic and renal activities of ornithine aminotrans-ferase (OAT) [L-ornithine 2-oxoacid aminotransferase, EC 2.6.1.13] were determined in male and female rats given diet with or without pyridoxine. OAT activities were measured in the presence of pyridoxal phosphate. Diet without pyridoxine caused a decrease in hepatic OAT activity in males and no change in females and an increase in renal OAT activity in males and a decrease in females. The increased renal OAT activity in males was associated with increased immunochemically recognizable OAT, and was due to increased synthesis of OAT as shown by measurement of [3H]leucine incorporation in vivo . Thus OAT is regulated by nutritional conditions in different ways in liver and kidney.
关键词：hepatic and renal OAT;synthesis of OAT;pyridoxine deficiency;pyridoxal phosphate;sexual difference
