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  • 标题:Physiological Impairment in Linoleic Acid Deficiency of Rats and the Effect of n-3 Polyunsaturated Fatty Acids
  • 本地全文:下载
  • 作者:Nobuko IRITANI ; Yumiko IKEDA ; Hitomi FUKUDA
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1984
  • 卷号:30
  • 期号:2
  • 页码:179-185
  • DOI:10.3177/jnsv.30.179
  • 出版社:Center for Academic Publications Japan
  • 摘要:Some impairments related to membrane function were found in linoleic acid-deficient rats and the effects of fish oil feeding were investigated. In linoleic acid-deficient rats, glucose transport into erythrocytes was decreased. The concentrations of plasma free fatty acids were significantly reduced in the animals. Further, epinephrine-stimulated lipase was remarkably less sensitive to epinephrine in the deficient rat than in the corn oil-fed control rat. However, these impairments were relieved by fish oil feeding. Therefore, the impairments may be ascribed to the decrease of arachidonic acid as a polyunsaturated fatty acid in membrane phospholipids, since n -3 polyunsaturated fatty acids appear to take the place of arachidonic acid. Key Words linoleic acid deficiency, fish oil, lipolysis, glucose transport
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