期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1982
卷号:28
期号:2
页码:149-162
DOI:10.3177/jnsv.28.149
出版社:Center for Academic Publications Japan
摘要:A study was undertaken to measure the ability of rats to regulate amino acid intake by means of a self-selection method. Weanling rats were simultaneously offered a choice between a 10% casein diet or a 10% amino acid mixture diet lacking methionine or lysine and a 10 casein diet containing different levels of methionine or lysine over 2 weeks. Weight gain and food consumption of rats allowed a choice between the two diets were much greater than those of animals fed on the fixed diets with high levels of methionine or lysine added, and the self-selecting rats had the ability to take in amounts of methionine or lysine appropriate to meet the requirement. Methionine intakes of self-selecting rats were kept to a relatively narrow range (41-100 mg/day), but lysine intakes of self-selecting rats were wide-ranging (86-300 mg/day). It was demonstrated that methionine or lysine intake is closely regulated in rats given a choice of diets containing varied levels of methionine or lysine.