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  • 标题:Regulation of Amino Acid Intake in the Rat: Self-Selection of Methionine and Lysine
  • 本地全文:下载
  • 作者:Keiichiro MURAMATSU ; Masahiro ISHIDA
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1982
  • 卷号:28
  • 期号:2
  • 页码:149-162
  • DOI:10.3177/jnsv.28.149
  • 出版社:Center for Academic Publications Japan
  • 摘要:A study was undertaken to measure the ability of rats to regulate amino acid intake by means of a self-selection method. Weanling rats were simultaneously offered a choice between a 10% casein diet or a 10% amino acid mixture diet lacking methionine or lysine and a 10 casein diet containing different levels of methionine or lysine over 2 weeks. Weight gain and food consumption of rats allowed a choice between the two diets were much greater than those of animals fed on the fixed diets with high levels of methionine or lysine added, and the self-selecting rats had the ability to take in amounts of methionine or lysine appropriate to meet the requirement. Methionine intakes of self-selecting rats were kept to a relatively narrow range (41-100 mg/day), but lysine intakes of self-selecting rats were wide-ranging (86-300 mg/day). It was demonstrated that methionine or lysine intake is closely regulated in rats given a choice of diets containing varied levels of methionine or lysine.
  • 关键词:methionine;lysine;self-selection;intake regulation;weanling rats
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