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  • 标题:STUDIES ON MYOINOSITOL
  • 本地全文:下载
  • 作者:Ikuo NISHIGAKI ; Hirobumi OHAMA ; Misao OKUMURA
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1975
  • 卷号:21
  • 期号:4
  • 页码:271-275
  • DOI:10.3177/jnsv.21.271
  • 出版社:Center for Academic Publications Japan
  • 摘要:Both caffeine and theophylline, which were known to be potent inhibitors of cyclic-AMP phosphodiesterase, stimulated the incorporation of myoinositol into phosphatidylinositol in rat liver homogenate. However, cyclic-AMP had no effect. The effect of dibutyrylcyclic-AMP differed with different concentrations. These results suggest that the stimulation cannot be explained by the increase in the amount of cyclic-AMP. This view was supported by the fact that papaverine, cyclic-AMP phosphodiesterase inhibitor, did not stimulate the incorporation and imidazole, the phosphodiesterase stimulator, did not inhibit the incorporation, and that adenylcyclase stimulators, epinephrine and glucagon, did not stimulate the incorporation.
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