期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1975
卷号：21
期号：3
页码：163-167
DOI：10.3177/jnsv.21.163
出版社：Center for Academic Publications Japan
摘要：Susceptibility to some antagonists of vitamin B6 was studied in frogs and cockroaches after operational intervention in their central nervous systems, and also in the intact frogs and cockroaches. Thiosemicarbazide, semicarbazide, isoniazide and penicillamine induced wild jumping behavior, and tonic or clonic convulsions in frogs, when the nervous parts posterior to the optic lobe inclusive remained intact. In frog, in which the nervous parts anterior to the diencephalon inclusive had been removed, no convulsions were induced by castrix or 4-deoxy-pyridoxine in large doses. In cockroaches excessive fluttering of wings and convulsions upon administration of thiosemicarbazide following severance of the central nerve cord between the subesophageal and prothoracic ganglions were induced. Castrix was not a convulsant in the intact frogs and cockroaches.
