期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1995
卷号：41
期号：1
页码：151-161
DOI：10.3177/jnsv.41.151
出版社：Center for Academic Publications Japan
摘要：Rat cecal contents were static-cultured with three kinds of dietary fibers and examined for the production of short-chain fatty acids after 24 h of cultivation. The total amount and molar ratio of acetate, propionate and butyrate ( n =8) were 7.20±0.62 mM and 38: 19:43 with indigestible dextrin (ID), a low-viscosity, water-soluble dietary fiber, 10.88±0.46 mgt and 49: 5:46 with pectin (PE), a high-viscosity, water-soluble dietary fiber, and 1.83±0.19m and 64: 11:25 with corn fiber (CF), a water-insoluble dietary fiber, respectively (the corresponding values obtained with glucose were 10.59±0.37 mM and 15:27: 58). Next, rats were kept on a cholesterol- and bile acid-free high-sucrose diet. At the completion of the 8-week feeding period, the serum total-cholesterol levels were significantly lower, at 57.6±3.8 ( n =8), 63.2±4.67 ( n =7), and 77.8±3.7 mg/dl ( n =9), in the ID-, PE-, and CF-supplemented diet groups, respectively, than in the control group given no dietary fiber (92.7±3.8 mg/dl, n =7). The cecal propionate production was signifi-cantly increased in both the ID and PE groups, while the fecal excretion of bile acids was increased in all three fiber groups compared to the control group. In addition, there was a significantly negative correlation between the serum total-cholesterol level and cecal propionate production in the ID group, between the serum cholesterol level and bile acid excretion in the CF group, and between the serum cholesterol level and cecal propionate production or bile acid excretion in the PE group. These results suggest that the degree of intestinal fermentation and bile acid excretion, which are considered to be associated with the hypocholesterol-emic action of dietary fiber, varies with each kind of dietary fiber.
