期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1988
卷号：34
期号：6
页码：587-594
DOI：10.3177/jnsv.34.587
出版社：Center for Academic Publications Japan
摘要：To clarify whether capsaicin or Isothiocyanate, which are found in common spices, activate brown adipose tissue (BAT) function, BAT temperature, mitochondrial guanosine diphosphate (GDP) binding (a thermogenic indicator), and mitochondrial oxygen consumption were measured in Interscapular brown adipose tissue (IBAT) of rats. Intramuscular injection of capsaicin (0.7mg/kg) or Isothiocyanate (3.0mg/kg) increased significantly IBAT temperature without affecting the rectal temperature, a possible side effect, and increased significantly GDP binding and mitochondrial oxygen consumption in IBAT, as did adminis-tration of ephedrine (0.375mg/kg). Therefore, the administration of capsaicin or Isothiocyanate activates BAT function in rats.
