期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1988
卷号：34
期号：4
页码：353-362
DOI：10.3177/jnsv.34.353
出版社：Center for Academic Publications Japan
摘要：The effects of low protein intake on protein metabolism, including the size of pools and the protein synthesis rates, were studied by use of [15N] glycine in Papua New Guinea highlanders. Studies were made on 9 men between October and December in 1982. In experiment 1, two subjects were given a protein-free diet (PFD) containing 49.1 kcal/kg of energy. In experiment 2, subjects were given a sweet-potato diet (SPD) containing 45.4kcal/kg of energy and 0.507g/kg of protein for 8 days, and then were given a low-protein sweet-potato diet (LPSPD) containing 50.0 kcal/.kg of energy and 0.265g/kg of protein. During the SPD period, the sizes of the metabolic and active protein pools (mean±SD) were 270±134mgN/kg and 362±107mgN/kg, respectively, and the rates of active and inactive protein synthesis were 463±161 mgN/kg/day and 299±38mgN/kg/day, respectively. During the LPSPD period, the sizes of the metabolic pool and active protein pool were 131±64 mgN/kg and 378±106mgN/kg, respectively, and the rates of active and inactive protein synthesis were 490±206mgN/kg/day and 280±26mgN/kg/day, respectively. The protein metabolism in the LPSPD showed no significant difference from the SPD. The results suggest that, when the energy levels were approximately the same, protein metabolism in Papua New Guinea highlanders was maintained in spite of the decrease in protein intake.
关键词：Papua New Guinea highlanders;protein metabolism;[15N]glycine;protein metabolic pool;protein synthesis rate
