期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1973
卷号：19
期号：4
页码：289-294
DOI：10.3177/jnsv.19.289
出版社：Center for Academic Publications Japan
摘要：The effects of riboflavin deficiency on serum proteins have been studied in rats following protein depletion and repletion with high-protein diet. Riboflavin deficiency causes a reduced serum total protein con-centration, reflecting changes in all fractions except β-globulin. The decrease in serum total protein level with changes in albumin and γ-globulin fractions following protein depletion is less pronounced in riboflavin deficiency. Although these changes are reversed upon repletion with 40% protein diet, the values of serum total protein and its different fractions with the exception of a2- and β-globulins in ribo-flavin-deficient rats are still lower than those of control rats undergoing the same dietary treatment. It has been suggested that lowered serum protein level in riboflavin deficiency on 16% protein diet or on repletion with 40% protein diet following protein depletion may result from reduced synthesis by the liver as well as increased utilization by the peripheral tissues.
