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  • 标题:Decreased Blood Levels of Lactic Acid and Urinary Excretion of 3-Methylhistidine after Exercise by Chronic Taurine Treatment in Rats
  • 本地全文:下载
  • 作者:Sachinobu MANABE ; Ikuyo KURODA ; Kazuko OKADA
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:2003
  • 卷号:49
  • 期号:6
  • 页码:375-380
  • DOI:10.3177/jnsv.49.375
  • 出版社:Center for Academic Publications Japan
  • 摘要:Taurine is reported to increase contractility of skeletal muscle and cardiac myocyte, which can increase exercise performance. The present study aimed to clarify taurine's effect on chronic endurance exercise, especially accumulation of lactic acid (LA), a marker of fatigue and ability of aerobic exercise, and urinary secretion of 3-methylhistidine (3-MH), a marker of muscle breakdown in rats. After exercise blood levels of LA and urinary excretion of 3-MH were significantly increased and this increase was significantly less in those with chronic treatment of taurine. Taurine treatment also significantly decreased fat accumulation and blood levels of cholesterol and triglyceride, which might improve insulin resistance and utilization of fat and glucose. These results indicate taurine treatment is useful for reducing physical fatigue and muscle damage during exercise training in rats, presumably due to antioxidant property and improvement of muscle and cardiac functions by taurine.
  • 关键词:taurine;lactate threshold;lactic acid;3-methylhistidine;exercise
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