期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1997
卷号：43
期号：4
页码：445-454
DOI：10.3177/jnsv.43.445
出版社：Center for Academic Publications Japan
摘要：The response of the bowel mucosa to enteral formula supplemented with dietary fiber was examined in rats with 30% full-thickness burns. The rats were fed a standard enteral formula without fiber or with one of two types of fiber (insoluble soy fiber or soluble guar gum fiber). Seventy-two hours after burn injury, the mesenteric lymph nodes were excised aseptically for bacterial culturing. Samples of the jejunum, ileum and cecum were also collected for histological examination. There were significantly fewer bacterial colonies in the lymph node cultures from rats given soy fiber compared to those from rats fed no fiber. In rats given soy fiber, the integrity of the bowel mucosa was maintained in the jejunum, ileum and cecum. In rats given guar gum fiber, however, the repair of mucosal erosions was observed in the jejunum and ileum as well as flattening of the cecal mucosa. These findings indicate that soy fiber is superior to guar gum fiber for maintaining bowel mucosal integrity and preventing bacterial translocation in burned rats receiving enteral feeding.
