期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1989
卷号：35
期号：6
页码：579-588
DOI：10.3177/jnsv.35.579
出版社：Center for Academic Publications Japan
摘要：An α-amylase inhibitor prepared from cranberry bean ( Phaseolus vulgaris ) was examined for its in vivo action on pancreatic α-amylase in rat small intestine. For this purpose, postprandial changes not only in intraluminal α-amylase activity but also in plasma glucose and insulin concentrations were measured at various times after administration of 2 g of 10% polyethylene glycol-containing experimental diets with and without the inhibitor. No considerable increase was observed in the levels of intraluminal α-amylase activity, blood sugar, and plasma insulin in the animals given the inhibitor at a dose of 10 mg each. These results suggest that the purified preparation from cranberry bean serves in fact as a potent inhibitor of rat pancreatic α-amylase.
