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  • 标题:Effect of Individual Amino Acids on Plasma Cholesterol Level in Rats Fed a High Cholesterol Diet
  • 本地全文:下载
  • 作者:Kimio SUGIYAMA ; Masayuki MIZUNO ; Keiichiro MURAMATSU
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1986
  • 卷号:32
  • 期号:6
  • 页码:623-633
  • DOI:10.3177/jnsv.32.623
  • 出版社:Center for Academic Publications Japan
  • 摘要:The effect of individual amino acids added to a cholesterol containing casein diet on the plasma cholesterol level of rats was systematically investigated with objective of confirming the possibility that specific amino acids are responsible for the regulation of plasma cholesterol level by dietary proteins. Half the amino acids tested were effective to some degree in influencing the plasma cholesterol level when amino acids were added singly to the diet at a 5% level. However, only sulfur containing amino acids had significant effects when added to the diet at a 1% level; Met enhanced and Cys reduced the plasma cholesterol level. In addition, the results of an experiment with amino acid mixture diets with different Met, Cys, and/or Gly contents indicated the importance of sulfur amino acids and also of Gly in plasma cholesterol regulation. The results obtained here support the notion that the plasma cholesterol level of rats can be influenced by specific amino acids or amino acid compositions of dietary proteins, at least under the experimental conditions used.
  • 关键词:plasma cholesterol;amino acid supplementation;methionine;cystine;glycine
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