文章基本信息

标题：METABOLISM OF INJECTED FLAVINS STUDIED BY USING DOUBLE-LABELED [14C] FLAVIN ADENINE DINUCLEOTIDE AND [14C, 32P] FLAVIN MONONUCLEOTIDE
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作者：Jun OKUDA ; Junko NAGAMINE ; Misao OKUMURA 等
期刊名称：Journal of Nutritional Science and Vitaminology
印刷版ISSN：0301-4800
电子版ISSN：1881-7742
出版年度：1978
卷号：24
期号：5
页码：505-510
DOI：10.3177/jnsv.24.505
出版社：Center for Academic Publications Japan
摘要：The metabolism of flavins in mouse was studied with [F-(2)-¹⁴C, A-(2, 8)-¹⁴C] FAD and [F-(2)-¹⁴C, ³²P] FMN. Ninety minutes after injection, radioactive isoalloxazine nucleus of double-labeled FAD was markedly incorporated into FAD, FMN and riboflavin in the liver, whereas a small amount of radioactive adenine nucleus of double-labeled FAD was found in FAD in the liver. In the case of FMN, radioactive isoalloxazine nucleus of double-labeled FMN was markedly incorporated into FAD, FMN and riboflavin in the liver, whereas only a minute amount of radioactive phosphorus was incorporated into FMN and FAD in the same organ. These results indicate that FMN and FAD injected are rapidly hydrolyzed and resynthesized in animal body.