期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1973
卷号:19
期号:4
页码:361-368
DOI:10.3177/jnsv.19.361
出版社:Center for Academic Publications Japan
摘要:The relative turnover rate of protein components of the thin filament was measured by a continuous double isotope method. Both 3H-lysine and 14C-lysine were administered continuously in the diet to male adult rabbits for 7 days. On the 7th day, the 14C-lysine was discontinued while the 3H-lysine was continued for 14 additional days. The relative turnover rate of the protein components was estimated from the 3H/14C ratios of the isolated protein of the same animal. From the different ratios of 3H/14C of each protein fraction, asynchronous turnover of the thin fila-ment proteins (actin, tropomyosin and troponin) was concluded. The order of degree in relative turnover rate is as follows: troponin>tropomyosin>actin.