期刊名称:Journal of Nutritional Science and Vitaminology
印刷版ISSN:0301-4800
电子版ISSN:1881-7742
出版年度:1973
卷号:19
期号:2
页码:183-186
DOI:10.3177/jnsv.19.183
出版社:Center for Academic Publications Japan
摘要:The effect of vitamin D on the metabolism of Ca and P has been studied in-tensively for many years, and is still under active investigation ( 1 ). There is the possibility, however, that it may affect, directly or indirectly, aspects of metabolism other than mineral. For example, since ergocalciferol is known to influence citrate metabolism ( 2 ) it may affect the metabolism of other substances such as fatty acids. It has been shown recently ( 3-5 ) in fact, that the administration of ergocalciferol to rachitic rats increases the uptake of 32P-orthophosphate by the phospholipids of the intestinal mucosa, liver, and kidney, and that it increases the triglyceride content of bone ( 6 ). Although toxic doses of vitamin D do not influence the proportions of the various fatty acids in the livers of rachitic rats ( 7 ), it would be of interest to know whether nontoxic levels of vitamin D would influence fatty acid distribution in the triglycerides significantly, and thus perhaps indirectly influence the structure of the cell membranes in areas critical for Ca absorption ( 8 ).