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  • 标题:EFFECT OF VITAMIN D3 ON LIVER FATTY ACIDS IN THE CHICK
  • 本地全文:下载
  • 作者:C. PAREKH ; R. H. WASSERMAN
  • 期刊名称:Journal of Nutritional Science and Vitaminology
  • 印刷版ISSN:0301-4800
  • 电子版ISSN:1881-7742
  • 出版年度:1973
  • 卷号:19
  • 期号:2
  • 页码:183-186
  • DOI:10.3177/jnsv.19.183
  • 出版社:Center for Academic Publications Japan
  • 摘要:The effect of vitamin D on the metabolism of Ca and P has been studied in-tensively for many years, and is still under active investigation ( 1 ). There is the possibility, however, that it may affect, directly or indirectly, aspects of metabolism other than mineral. For example, since ergocalciferol is known to influence citrate metabolism ( 2 ) it may affect the metabolism of other substances such as fatty acids. It has been shown recently ( 3-5 ) in fact, that the administration of ergocalciferol to rachitic rats increases the uptake of 32P-orthophosphate by the phospholipids of the intestinal mucosa, liver, and kidney, and that it increases the triglyceride content of bone ( 6 ). Although toxic doses of vitamin D do not influence the proportions of the various fatty acids in the livers of rachitic rats ( 7 ), it would be of interest to know whether nontoxic levels of vitamin D would influence fatty acid distribution in the triglycerides significantly, and thus perhaps indirectly influence the structure of the cell membranes in areas critical for Ca absorption ( 8 ).
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