出版社:National Institute of Occupational Safety and Health
摘要:By acute exposure of dogs to 1, 1, 1-trichloroethane and observing the changes in hematologic parameters during and after exposure, the following results were obtained. A marked but temporary decrease in leukocytes was noted 30 minutes after the start of exposure, but no change was observed in the erythrocytes, hematocrit values or thrombocytes. According to leukocyte differential counts, all types of leukocytes showed a decrease. The decrease in neutrophils was particularly pro-minent. A dose-response relationship was seen between the exposure concentrations of 1, 1, 1-trichloroethane from 200 to 700 ppm. and the grade of decrease in leuko-cyte counts.