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  • 标题:ORGAN DISTRIBUTION OF MERCURY VAPOR INHALED BY ACATALASEMIA AND HYPOCATALASEMIA MICE
  • 本地全文:下载
  • 作者:Masana OGATA ; Seiko KANEMATSU ; Keijiro MORITA
  • 期刊名称:Industrial Health
  • 印刷版ISSN:0019-8366
  • 电子版ISSN:1880-8026
  • 出版年度:1981
  • 卷号:19
  • 期号:4
  • 页码:241-246
  • DOI:10.2486/indhealth.19.241
  • 出版社:National Institute of Occupational Safety and Health
  • 摘要:Acatalasemia and hypocatalasemia mice had decreased levels of mer-cury in the lung and blood and increased levels in the liver following exposure in vivo to metallic mercury vapor (1.4 mg/m3 for 2 hours). The decreased uptake of mercury was roughly proportional to the decrease in catalase activity in these organs. Acatalasemia mice injected with ethyl alcohol showed a decrease in the mercury content of the lung and blood and an increase in the liver content in com-parison with non-treated acatalasemia mice. The inhibitory effect of ethyl alcohol on the uptake of mercury was considered to derive from the peroxidase action of catalase with ethyl alcohol as substrate.
  • 关键词:Key words : Hypocatalasemia mice;Acatalasemia mice;Metallic mercury uptake;Catalase
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