出版社:National Institute of Occupational Safety and Health
摘要:Two methods for recording oscillatory movements in mice have been developed. The first method uses a permanent dynamic speaker, on which a mouse cage is placed. The second one is an assembly consisting of an accelerometer using strain gauges, a small bar for placing the mouse on it and attaching the accelerometer and a support-ing stand for the bar. The output from the speaker or the accelerometer is fed to an apparatus for electroencephalography or to a tape recorder. The data stored in the tape are analyzed by an electric filter. Tremorine was used as an inducing agent for oscillatory movements. Tremor in-duced by tremorine was characterized as follows: (1) the increase of immobile periods, (2) the derease of movements with high frequencies such as over 25 cps, and (3) the intermittent appearance of movement with specific frequencies between 14-25 cps. From the viewpoint of easiness in finding tremor, the second method has been considered to be better than the first, because of a clear discriminative ability for tremor from other oscillatory movements recorded.