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  • 标题:INTERACTION BETWEEN QUERCETIN AND SUPEROXIDE RADICALS. REDUCTION OF THE QUERCETIN MUTAGENICITY
  • 本地全文:下载
  • 作者:IKUKO UENO ; MASAHIRO KOHNO ; KIMIE HARAIKAWA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1984
  • 卷号:7
  • 期号:11
  • 页码:798-803
  • DOI:10.1248/bpb1978.7.798
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Interaction between quercetin and superoxide radicals was investigated using xanthine-xanthine oxidase system and potassium superoxide as superoxide radical generators. Superoxide radical scavenging action of quercetin was demonstrated by measurement of the electron spin resonance spectrum of the 5-hydroperoxy-2, 2-dimethyl-1-1pyrrolidinyloxyl adduct. Degradation of quercetin by the radicals was demonstrated spectrophotometrically. Reduction of the quercetin mutagenicity by the radicals was demonstrated in the Salmonella typhimurium strain TA 98 by the Ames test.
  • 关键词:flavonoid
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