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  • 标题:EFFECTS OF DIAZEPAM, MEPROBAMATE, CHLORPROMAZINE AND APOMORPHINE ON A QUICKLY LEARNED CONDITIONED SUPPRESSION IN MICE
  • 本地全文:下载
  • 作者:MITSUAKI NAGASAKA ; TSUTOMU KAMEYAMA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1983
  • 卷号:6
  • 期号:8
  • 页码:523-526
  • DOI:10.1248/bpb1978.6.523
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Mice exhibited a marked suppression of motor activity when placed into the same environment in which they had previously received electric foot shocks. Apomorphine-HCl (0.1-10 mg/kg) produced a dose-dependent reduction of the conditioned suppression of activity, but did not increase activity in non-shocked mice. Diazepam (0.2, 1, and 5 mg/kg), meprobamate (25 and 50 mg/kg), and chlorpromazine-HCl (2 and 5 mg/kg) did not reduce conditioned suppression. Thus, the conditioned suppression caused by a quick conditioning technique does not produce similar results to those using the conditioned emotional response involving suppression of operant lever-pressing behavior.
  • 关键词:mice
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