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  • 标题:COVALENT BINDING OF CEFOTAXIME TO HUMAN SERUM ALBUMIN
  • 本地全文:下载
  • 作者:TOSHIMASA TOYO'OKA ; AKIMITSU SANO ; TAKEO KURIKI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1983
  • 卷号:6
  • 期号:2
  • 页码:139-140
  • DOI:10.1248/bpb1978.6.139
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The covalent binding ratio of cephalosporins (CEZ, CER, CET and CTX) to human serum albumin was examined at pH 7 and pH 10. The antibiotic equivalents were larger at pH 10 than at pH 7. The degree in the binding ratio of the 4 cephalosporins was CET>CER>CTX>CEZ at pH 7 and CER>CET>CTX>CEZ at pH 10.
  • 关键词:human serum albumin
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