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  • 标题:BIOLOGICALLY ACTIVE PRINCIPLES OF CRUDE DRUGS. II. ANTI-ALLERGIC PRINCIPLES IN "SHOSEIRYU-TO" ANTI-INFLAMMATORY PROPERTIES OF PAEONIFLORIN AND ITS DERIVATIVES
  • 本地全文:下载
  • 作者:JOHJI YAMAHARA ; TOSHIO YAMADA ; HITOSHI KIMURA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1982
  • 卷号:5
  • 期号:11
  • 页码:921-929
  • DOI:10.1248/bpb1978.5.921
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Anti-inflammatory properties of paeoniflorin and its derivatives were examined in experimental animals. Paeoniflorin, desbenzoylpaeoniflorin and new monoterpene glucoside 'paeonon' inhibited experimental contact hypersensitivities and passive cutaneous anaphylaxis reaction. Paeonon inhibited tissue swelling in the adjuvant arthritis, while paeoniflorin and its related compounds were ineffective in inhibiting non-allergic inflammatory response.
  • 关键词:new monoterpene glucoside 'paeonon'
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