摘要:High concentrations of propranolol (10-5-3×10-4M) inhibited in a dosedependent fashion and reversibly the maximal contractile responses produced by 150 mM K+ in the rat vas deferens. 10-4M propranolol and quinine produced similar inhibitory effects on the dose-response curves to K+. Since norepinephrine-induced contractions were not substantially inhibited by quinine or propranolol, it was suggested that the two drugs may specifically inhibit the potassium-induced inflow of external calcium.