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  • 标题:OCCURRENCE OF LOOSELY BOUND MERCURY IN THE BLOOD OF GUINEA PIG TREATED WITH METHYLMERCURIC CHLORIDE
  • 本地全文:下载
  • 作者:YUTAKA UDA ; YASUO NAKAZAWA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1979
  • 卷号:2
  • 期号:4
  • 页码:245-250
  • DOI:10.1248/bpb1978.2.245
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Guinea pigs were given 203Hg-labeled methylmercuric chloride or mercuric chloride and then the distribution of mercury in the blood, brain and liver was investigated. The methylmercury in the blood and brain was extracted with a chloroform-methanol mixture. Most of the extractable mercury from the blood was detected in the proteolipid fraction by further fractionation. The mercury in the chloroform-methanol extract was also dialyzable against the same solvent. These findings suggest the occurrence of loosely bound mercury in the blood after administration of methylmercury.
  • 关键词:proteolipid
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