标题：INHIBITORY ACTION OF 2-(1, 2-BENZISOXAZOL-3-YL)-3-[2-(2-PIPERIDINOETHOXY)PHENYL]ACRYLONITRILE (SX-284) ON ACETYLCHOLINE RELEASE FROM VAGUS NERVE IN GUINEA PIG ILEUM
摘要：Newly synthesized compound, 2-(1-, 2-benzisoxazol-3-yl)-3-[2-(2-piperidinoethoxy)phenyl]acrylonitrile (SX-284) inhibited electrically evoked acetylcholine release from the stores in the myenteric plexus-longitudinal strips of guinea pig ileum which was labelled with [3H]-choline but not the evoked release of tracer from rat vas deferens after labelling with [3H]-norepinephrine. These results support our previous findings that SX-284 specifically inhibit acetylcholine release from the vagus nerve in the gastrointestinal canal.
