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  • 标题:EFFECTS OF BUTYLATED HYDROXYTOLUENE (BHT) ON THE LEVEL OF GLUTATHIONE AND THE ACTIVITY OF GLUTATHIONE-S-TRANSFERASE IN RAT LIVER
  • 本地全文:下载
  • 作者:YOSHIO NAKAGAWA ; KOGO HIRAGA ; TETSUYA SUGA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1981
  • 卷号:4
  • 期号:10
  • 页码:823-826
  • DOI:10.1248/bpb1978.4.823
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Oral administration of 500 mg/kg of butylated hydroxytoluene (BHT) daily for three days elevated the total glutathione (GSH) level and the activities of GSH-S-transferase for CDNB and DCNB and GSSG reductase in the rat liver. BHT-alcohol, which is a metabolite of BHT, also elevated the level or activity of these components. The induction of these components with BHT-alcohol was slightly less than that with BHT. However, BHT or BHT-alcohol in doses used had no effect on GSH peroxidase activity.
  • 关键词:glutathione-S-transferase
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