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  • 标题:CHARACTERIZATION OF MUTAGENIC PRINCIPLES AND CARCINOGENICITY TEST OF DILL WEED AND SEEDS
  • 本地全文:下载
  • 作者:MASAMICHI FUKUOKA ; KUNITOSHI YOSHIHIRA ; SHINSAKU NATORI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1980
  • 卷号:3
  • 期号:5
  • 页码:236-244
  • DOI:10.1248/bpb1978.3.236
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Among the various kinds of spices tested, the aqueous extracts of dill weed from Anethum graveolens L. and dill seeds from A. sowa D.C. (Umbelliferae), exhibited a mutagenicity to Salmonella typhimurium, strains TA98 and TA100. The aqueous methanol extracts were fractionated by the mutation assay using the strain TA98 with S-9 Mix. Isorhamnetin 3-sulfate (persicarin) and quercetin 3-sulfate were characterized as the mutagenic principles. Carcinogenicity was not observed for dill weed and seeds when the diets containing these in 33% were administered for 450 and 410 days, respectively, to the inbred strain ACI rats.
  • 关键词:carcinogenicity test
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