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  • 标题:EFFECT OF CIANIDANOL (KB-53) ON THE ACTIVITY OF MOUSE NATURAL KILLER CELLS
  • 本地全文:下载
  • 作者:YOSHIAKI IKEDA ; KIYOTAKA KAWAKAMI ; IWAO SATO
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1984
  • 卷号:7
  • 期号:1
  • 页码:21-23
  • DOI:10.1248/bpb1978.7.21
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The effect of cianidanol (KB-53) on the mouse natural killer (NK) cell activity of the splenic cells was investigated using YAC-l cells as target cells. The oral administration of KB-53 at a dose of 500 mg/kg augmented significantly the NK cell activity. The activity was observed maximally 3 d after the administration, and significant difference from the control was observed even at 7 d after the administration of KB-53. The oral administration of KB-53, at a dose range of 125-500 mg/kg, augmented the NK cell activity in a dose dependent manner at 3d after the administration
  • 关键词:splenic cell
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