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  • 标题:EFFECTS OF LIMBIC LESIONS, ESPECIALLY OF OLFACTORY BULBECTOMY ON SIMPLE CONDITIONED AVOIDANCE RESPONSE IN RATS
  • 本地全文:下载
  • 作者:YUTAKA GOMITA ; SHOWA UEKI
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1980
  • 卷号:3
  • 期号:2
  • 页码:94-104
  • DOI:10.1248/bpb1978.3.94
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Effects of olfactory bulbectomy, and lesions of the septum and dorsal hippocampus on emotionality as well as on the simple conditioned avoidance response in a two-way shuttle box were investigated in rats. The rats with bilateral olfactory bulbectomy (O.B. rats) showed hyperactivity and aggressive behavior, including mouse-killing behavior (muricide), and those with septal lesions exhibited hyperreactivity and hypoactivity, while the rats with hippocampal lesions became hypoactive without showing hyperreactivity. The O.B. and septal rats, on an average, showed a facilitation in acquisition of the conditioned avoidance response and a retardation in extinction. The muricidal group of O.B. rats, however, showed slower acquisition, while the nonmuricidal O.B. rats showed much faster acquisition and slower extinction than intact rats. Hippocampal lesions retarded acquisition.
  • 关键词:conditioned avoidance
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