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  • 标题:ENHANCEMENT OF LYMPHATIC TRANSPORT OF 1-(2-TETRAHYDROFURYL)-5-FLUOROURACIL BY WATER-IN-OIL EMULSION
  • 本地全文:下载
  • 作者:YASUO NAKAMOTO ; TOSHIYUKI TAKEEDA ; FUMIYO SAKIKAWA
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:1979
  • 卷号:2
  • 期号:1
  • 页码:45-51
  • DOI:10.1248/bpb1978.2.45
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Enhancement of the lymphatic transport of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207), an orally active anticancer agent, was demonstrated by the administration of W/O emulsion into the loop of rat small intestine. The lymphatic transport of FT-207 was inhibited by the presence of bile. Absorption of oil in the absence of bile was confirmed by light microscopy. Electron micrograph revealed that oil droplets are mainly transported via the lymphatic system.
  • 关键词:electron micrograph
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