摘要：Benzalkonium chloride used as detergents and disinfectants was readily analyzed by gas chromatography (GC) of their reduction products obtained by their treatment with NaBH4 and NiCl2. The reduction products of benzalkonium chloride (alkyldimethylbenzylammonium chloride) were identified as alkyldimethylamines (I-VI) by GC-mass spectrometry. In the reduction, the benzyl groups of alkyldimethylbenzylammonium chloride was eliminated as toluene. The procedure is applicable for characterizing the distribution of long chain alkyl groups in benzalkonium chloride, and suited for the assay of 10-100 μg/ml aqueous solution of benzalkonium chloride (mainly consisting of the n-C12H25, n-C14H29 and n-C16H33 homolog components : Zephiran). Furthermore, the procedure is very useful for routine analysis of benzalkonium chloride since the reduction takes place smoothly by the use of NaBH4 and NiCl2 which are relatively safe to handle and inexpensive, instead of a complicated apparatus and expensive catalyst in catalytic hydrogenation.
关键词：benzalkonium chloride;N-alkyldimethylbenzylammonium chloride;detergents;disinfectants;reduction products of N-alkyldimethylbenzylammonium chloride;N-alkyldimethylamine;gas chromatography;reduction system of NaBH4 and NiCl2
