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  • 标题:ローズベンガルとのイオン会合を利用した尿中メタンフェタミンのスクリーニング法
  • 本地全文:下载
  • 作者:庄山 正敏 ; 佐野 敏幸
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:1985
  • 卷号:31
  • 期号:6
  • 页码:410-413
  • DOI:10.1248/jhs1956.31.410
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Methamphetamine was found to form an ion-associated complex with rose bengal (RB) by shaking with 1 ml of 0.1% RB solution in the presence of bromphenol blue to prevent the interfering of RB layer. The complex was successfully extracted with dichloromethane at pH 7.3 and gave yellowish orange fluorescence under UV light. The limit of detection of methamphetamine determined by the aid of the fluorescence of the extracted layer was 0.2 μg in aq. solution and 0.6 μg in the urine. This method was applied to the screening test for urine specimens of methamphetamine-abuse suspects and satisfactory results were obtained.
  • 关键词:methamphetamine screening method;rose bengal;ion association;fluorescence detection
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