摘要：To examine the mechanism of the enhancement of tocopherol concentration in the testis of rats when the inflammation was induced by CdCl2 administration, we measured concentrations of tocopherol homologues in the serum, liver and testis of CdCl2-treated rats as a function of time. In the serum, α-and β-tocopherol concentrations increased significantly at 15 h after CdCl2 administration, and those levels in the testis increased significantly at 24 h or 48 h after the metal administration. No significant change of the concentrations of tocopherols in the liver was seen by CdCl2 administration. On the other hand, the incorporations of 3H-α-tocopherol into the testis and the epididymis, when injected into the rat treated with CdCl2, increased 6-and 8-fold as compared with those in control rats, respectively. These results indicate that α-tocopherol is actively incorporated into the inflammed testis via blood stream.
