摘要：Following the preceeding work on the acute and subacute toxicity tests of cadmium chloride, metabolism and organ distribution of cadmium chloride in rats were investigated after continuous oral administration of 5 or 20 mg/kg/day of cadmium chloride for 30 days. Most of the administered cadmium chloride was excreted in feces and only less than 0.1% was detected in urine. The amount of accumulation of cadmium chloride was highest in the liver, followed by kidney, pancreas, and spleen in that order. Examination of calcium and phosphate excreted in urine and feces showed that the amount of discharged calcium increased markedly in proportion to that taken, while the amount of phosphate excreted in urine and feces decreased. As for the distribution pattern of calcium and phosphate, a clear change could not be observed in the group administered cadmium.
