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  • 标题:有機水銀化合物の毒性(第1報) : 塩化メトキシエチル水銀による水俣病様症状の発現
  • 本地全文:下载
  • 作者:石倉 俊治 ; 井上 典子 ; 与那覇 政憲
  • 期刊名称:Journal of Health Science
  • 印刷版ISSN:1344-9702
  • 电子版ISSN:1347-5207
  • 出版年度:1971
  • 卷号:17
  • 期号:1
  • 页码:33-37
  • DOI:10.1248/jhs1956.17.33
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Diet mixed with different organic mercury compounds was fed continuously to dd strain male mice and mercury content in organs was estimated photometrically by the dithizone method after wet digestion of samples with nitric and sulfuric acids. Significant difference was observed in growth curves of mice given MEMC in doses of 1250 and 2500μg Hg/day from that of the control, and specific neural symptoms were observed in almost all the animals. In the case of MEMC, mercury content in the organs was the highest in the liver, followed by the kidney, spleen, and brain, in the decreasing order. Accumulation of mercury in the liver increased with an increasing dose, but no variation in the amount of accumulated mercury was observed in the kidney. In the case of BMC, accumulation of mercury in the brain was higher than that of MEMC.
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