摘要:Decreasing tendency of the activity of palmar disinfectants is important in their practical use. The decrease of disinfecting activity of some antiseptic solutions by standing at room temperature (23∼32°) was examined by the phenol coefficient test using Serratia marcescens. It took 10 days for the phenol coefficients of liquefied phenol and saponated cresol solution. and took more than 20 days for those of benzalkonium chloride and mercuric chloride solutions to decrease to the half of the initial coefficient. Among the activity of these four antiseptic solutions, that of benzalkonium chloride solution was most markedly decreased by hand-washing.