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  • 标题:Organic Phosphates. II. Studies on Hydrolysis of Several Cyclic Phosphates.
  • 本地全文:下载
  • 作者:Tyunosin Ukita ; Kinzo Nagasawa ; Masachika Irie
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1957
  • 卷号:5
  • 期号:2
  • 页码:127-132
  • DOI:10.1248/cpb1953.5.127
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Synthesized glycerol 1, 2-cyclic phosphate (GCP) was hydrolysed to glycerol-1 and -2 phosphate under both acid and alkaline conditions and from the quantitative estimation of the resulting glycerol-1 phosphate, the mode of hydrolytic reaction of glycerophos-phorylcholine was discussed. Synthetic 1, 2-propanediol cyclic phosphate (PCP) was found to give only 1, 2-propanediol-1 phosphate after hydrolysis under tested acid and alkaline conditions. GCP, PCP, synthetic ethyleneglycol cyclic phosphate (ECP), and 2, 3-butanediol cyclic phosphate (BCP) were tested for their stabilities to hydrolysis at various pHs.
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