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  • 标题:Metabolism of Drugs. VIII.2) The Metabolic Fate of Methylhexabital (5-Cyclohexenyl-3, 5-dimethylbarbituric Acid).(4). Ultraviolet and Infrared Absorption Spectra of the Metabolites of MHB and Related Compounds
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  • 作者:Hisao TSUKAMOTO ; Hidetoshi YOSHIMURA ; Satoshi TOKI
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:1956
  • 卷号:4
  • 期号:5
  • 页码:371-375
  • DOI:10.1248/cpb1953.4.371
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:The ultraviolet absorption spectra of the metabolites from the urine of rabbits receiving MHB, the oxidation products of MHB and nor-MHB with chromium trioxide were measured, and the relation between these compounds and their structures was discussed. The infrared absorption spectra of 3-keto-MHB and MHB-M (II) from the previous work in this series indicated that the two are completely identical and would be α, β-unsaturated ketones and that of 3-OH-MHB suggested the existence of a hydroxyl group in the structure.
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